1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride structure

1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride

TL;DR: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride (CAS 20357-37-3) is a chemical compound with molecular formula C19H15Cl2NO3 and molecular weight 375.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl chloride

Also Known As: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl chloride, 1h-indole-3-acetyl chloride, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetyl chloride, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetylchloride

CAS: 20357-37-3
Molecular Formula C19H15Cl2NO3
Molecular Weight 375.04 g/mol
LogP 5.3
Topological Polar Surface Area 48.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 375.0429
Heavy Atoms 25
Complexity 507.0

Chemical Identifiers

CAS Number 20357-37-3
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)Cl
InChIKey VCVWWGAKIXAYTN-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (28 patents) Organic Building Blocks (9 patents) Peptides & Amino Acids (2 patents) Pharmaceutical Intermediates (21 patents)

Product Overview

1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride (CAS 20357-37-3), with molecular formula C19H15Cl2NO3 and molecular weight 375.04 g/mol. IUPAC: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride

XLogP
5.3
TPSA (Topological Polar Surface Area)
48.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
25
Complexity
507.0
Exact Mass
375.0429
Monoisotopic Mass
375.0429
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride

The XLogP value of 5.3 indicates that 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.3 Ų, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride?

The CAS number of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride is 20357-37-3.

What is the molecular formula of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride?

The molecular formula of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride is C19H15Cl2NO3.

What is the molecular weight of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride?

The molecular weight of 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride is 375.04 g/mol.

Where can I buy 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride?

You can request a quote for 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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