2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile structure

2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile

TL;DR: 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile (CAS 20330-90-9) is a chemical compound with molecular formula C9H4F5N and molecular weight 221.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[2,3-difluoro-4-(trifluoromethyl)phenyl]acetonitrile

Also Known As: 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile, 2-(2,3-Difluoro-4-(trifluoromethyl)phenyl)acetonitrile, Dimethyl 5-chloroisophthalate, 2-[2,3-difluoro-4-(trifluoromethyl)phenyl]acetonitrile, [2,3-Difluoro-4-(trifluoromethyl)phenyl]acetonitrile

CAS: 20330-90-9
Molecular Formula C9H4F5N
Molecular Weight 221.03 g/mol
LogP 3.04968
Topological Polar Surface Area 23.79 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 221.02638
Heavy Atoms 15
Complexity 415.73648

Chemical Identifiers

CAS Number 20330-90-9
SMILES C1=CC(=C(C(=C1CC#N)F)F)C(F)(F)F

Product Overview

2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile (CAS 20330-90-9), with molecular formula C9H4F5N and molecular weight 221.03 g/mol. IUPAC: 2-[2,3-difluoro-4-(trifluoromethyl)phenyl]acetonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile

XLogP
3.04968
TPSA (Topological Polar Surface Area)
23.79
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
15
Complexity
415.73648
Exact Mass
221.02638
Monoisotopic Mass
221.02638
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile

The XLogP value of 3.04968 indicates that 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.79 Ų, 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile?

The CAS number of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile is 20330-90-9.

What is the molecular formula of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile?

The molecular formula of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile is C9H4F5N.

What is the molecular weight of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile?

The molecular weight of 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile is 221.03 g/mol.

Where can I buy 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile?

You can request a quote for 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile?

Yes, KEHONG BIO provides custom synthesis services for 2,3-Difluoro-4-(trifluoromethyl)phenylacetonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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