Tolpiprazole
TL;DR: Tolpiprazole (CAS 20326-13-0) is a chemical compound with molecular formula C17H24N4 and molecular weight 284.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3-methylphenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine
Also Known As: Tolpiprazole, Tolpiprazol, Tolpiprazole [INN:BAN], TOLPIPRAZOLE [INN], H 4170
| Molecular Formula | C17H24N4 |
|---|---|
| Molecular Weight | 284.20 g/mol |
| LogP | 2.39124 |
| Topological Polar Surface Area | 35.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 284.2001 |
| Heavy Atoms | 21 |
| Complexity | 581.98096 |
Chemical Identifiers
| CAS Number | 20326-13-0 |
|---|---|
| SMILES | CC1=CC(=CC=C1)N2CCN(CC2)CCC3=NNC(=C3)C |
Product Overview
Tolpiprazole (CAS 20326-13-0), with molecular formula C17H24N4 and molecular weight 284.20 g/mol. IUPAC: 1-(3-methylphenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine.
Chemical Property Profile of Tolpiprazole
Property Insights of Tolpiprazole
The XLogP value of 2.39124 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tolpiprazole. With a topological polar surface area (TPSA) of 35.16 Ų, Tolpiprazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tolpiprazole has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tolpiprazole?
The CAS number of Tolpiprazole is 20326-13-0.
What is the molecular formula of Tolpiprazole?
The molecular formula of Tolpiprazole is C17H24N4.
What is the molecular weight of Tolpiprazole?
The molecular weight of Tolpiprazole is 284.20 g/mol.
Where can I buy Tolpiprazole?
You can request a quote for Tolpiprazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tolpiprazole?
Yes, KEHONG BIO provides custom synthesis services for Tolpiprazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.