NIP142 structure

NIP142

TL;DR: NIP142 (CAS 203002-75-9) is a chemical compound with molecular formula C23H27N3O6 and molecular weight 441.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(3R,4S)-4-(cyclopropylamino)-3-hydroxy-2,2-dimethyl-7-nitro-3,4-dihydrochromen-6-yl]-2-(4-methoxyphenyl)acetamide

Also Known As: NIP142, NIP 142, SID:163563836, J1.709.572B, N-[(3R,4S)-4-(cyclopropylamino)-3-hydroxy-2,2-dimethyl-7-nitrochroman-6-yl]-2-(4-methoxyphenyl)acetamide

CAS: 203002-75-9
Molecular Formula C23H27N3O6
Molecular Weight 441.19 g/mol
LogP 3.1096
Topological Polar Surface Area 122.96 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 7
Rotatable Bonds 7
Exact Mass 441.18997
Heavy Atoms 32
Complexity 1032.7723

Chemical Identifiers

CAS Number 203002-75-9
SMILES CC1([C@@H]([C@H](C2=CC(=C(C=C2O1)[N+](=O)[O-])NC(=O)CC3=CC=C(C=C3)OC)NC4CC4)O)C

Product Overview

NIP142 (CAS 203002-75-9), with molecular formula C23H27N3O6 and molecular weight 441.19 g/mol. IUPAC: N-[(3R,4S)-4-(cyclopropylamino)-3-hydroxy-2,2-dimethyl-7-nitro-3,4-dihydrochromen-6-yl]-2-(4-methoxyphenyl)acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NIP142

XLogP
3.1096
TPSA (Topological Polar Surface Area)
122.96
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
7
Rotatable Bonds
7
Heavy Atoms
32
Complexity
1032.7723
Exact Mass
441.18997
Monoisotopic Mass
441.18997
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NIP142

The XLogP value of 3.1096 indicates that NIP142 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.96 Ų falls within the moderate polarity range, balancing permeability and solubility for NIP142. Following Lipinski's Rule of Five, NIP142 has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NIP142?

The CAS number of NIP142 is 203002-75-9.

What is the molecular formula of NIP142?

The molecular formula of NIP142 is C23H27N3O6.

What is the molecular weight of NIP142?

The molecular weight of NIP142 is 441.19 g/mol.

Where can I buy NIP142?

You can request a quote for NIP142 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NIP142?

Yes, KEHONG BIO provides custom synthesis services for NIP142 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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