CGH-1484A free base structure

CGH-1484A free base

TL;DR: CGH-1484A free base (CAS 202468-90-4) is a chemical compound with molecular formula C41H56FN7O6S2 and molecular weight 825.37 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-fluoroethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-6-[3-[4-(2-morpholin-4-yl-2-oxoethyl)piperazin-1-yl]-3-oxopropyl]-2,4-dihydro-1H-quinoline-8-sulfonamide

Also Known As: CGH-1484A free base, 8-Quinolinesulfonamide, N-((1S)-1-(2-benzothiazolylmethyl)-2-(4-(2-fluoroethyl)-1-piperidinyl)-2-oxoethyl)-1,2,3,4-tetrahydro-3,3-dimethyl-6-(3-(4-(2-(4-morpholinyl)-2-oxoethyl)-1-piperazinyl)-3-oxopropyl)-, Morpholine, 4-((4-(3-(8-((((1S)-1-(2-benzothiazolylmethyl)-2-(4-(2-fluoroethyl)-1-piperidinyl)-2-oxoethyl)amino)sulfonyl)-1,2,3,4-tetrahydro-3,3-dimethyl-6-quinolinyl)-1-oxopropyl)-1-piperazinyl)acetyl)-, Morpholine, 4-((4-(3-(8-(((1-(2-benzothiazolylmethyl)-2-(4-(2-fluoroethyl)-1-piperidinyl)-2-oxoethyl)amino)sulfonyl)-1,2,3,4-tetrahydro-3,3-dimethyl-6-quinolinyl)-1-oxopropyl)-1-piperazinyl)acetyl)-, (S)-, 3,3-Dimethyl-6-{3-[4-(2-morpholin-4-yl-2-oxo-ethyl)-piperazin-1-yl]-3-oxo-propyl}-1,2,3,4-tetrahydro-quinoline-8-sulfonic acid {(S)-1-benzothiazol-2-ylmethyl-2-[4-(2-fluoro-ethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide

CAS: 202468-90-4
Molecular Formula C41H56FN7O6S2
Molecular Weight 825.37 g/mol
LogP 3.7139
Topological Polar Surface Area 144.49 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 10
Rotatable Bonds 13
Exact Mass 825.37177
Heavy Atoms 57
Complexity 1988.988

Chemical Identifiers

CAS Number 202468-90-4
SMILES CC1(CC2=C(C(=CC(=C2)CCC(=O)N3CCN(CC3)CC(=O)N4CCOCC4)S(=O)(=O)N[C@@H](CC5=NC6=CC=CC=C6S5)C(=O)N7CCC(CC7)CCF)NC1)C

Product Overview

CGH-1484A free base (CAS 202468-90-4), with molecular formula C41H56FN7O6S2 and molecular weight 825.37 g/mol. IUPAC: N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-fluoroethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-6-[3-[4-(2-morpholin-4-yl-2-oxoethyl)piperazin-1-yl]-3-oxopropyl]-2,4-dihydro-1H-quinoline-8-sulfonamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of CGH-1484A free base

XLogP
3.7139
TPSA (Topological Polar Surface Area)
144.49
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
10
Rotatable Bonds
13
Heavy Atoms
57
Complexity
1988.988
Exact Mass
825.37177
Monoisotopic Mass
825.37177
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of CGH-1484A free base

The XLogP value of 3.7139 indicates that CGH-1484A free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 144.49 Ų indicates high polarity, suggesting CGH-1484A free base may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, CGH-1484A free base has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of CGH-1484A free base?

The CAS number of CGH-1484A free base is 202468-90-4.

What is the molecular formula of CGH-1484A free base?

The molecular formula of CGH-1484A free base is C41H56FN7O6S2.

What is the molecular weight of CGH-1484A free base?

The molecular weight of CGH-1484A free base is 825.37 g/mol.

Where can I buy CGH-1484A free base?

You can request a quote for CGH-1484A free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for CGH-1484A free base?

Yes, KEHONG BIO provides custom synthesis services for CGH-1484A free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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