2-Thiouridine
TL;DR: 2-Thiouridine (CAS 20235-78-3) is a chemical compound with molecular formula C9H12N2O5S and molecular weight 260.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one
Also Known As: 2-thiouridine, Uridine, 2-thio-, 3sfg, beta-2-thiouridine, THIOURIDINE
| Molecular Formula | C9H12N2O5S |
|---|---|
| Molecular Weight | 260.05 g/mol |
| LogP | -1.48261 |
| Topological Polar Surface Area | 107.71 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 260.0467 |
| Heavy Atoms | 17 |
| Complexity | 512.59796 |
Chemical Identifiers
| CAS Number | 20235-78-3 |
|---|---|
| SMILES | C1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Product Overview
2-Thiouridine (CAS 20235-78-3), with molecular formula C9H12N2O5S and molecular weight 260.05 g/mol. IUPAC: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one.
Chemical Property Profile of 2-Thiouridine
Property Insights of 2-Thiouridine
The XLogP value of -1.48261 indicates that 2-Thiouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 107.71 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Thiouridine. Following Lipinski's Rule of Five, 2-Thiouridine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Thiouridine?
The CAS number of 2-Thiouridine is 20235-78-3.
What is the molecular formula of 2-Thiouridine?
The molecular formula of 2-Thiouridine is C9H12N2O5S.
What is the molecular weight of 2-Thiouridine?
The molecular weight of 2-Thiouridine is 260.05 g/mol.
Where can I buy 2-Thiouridine?
You can request a quote for 2-Thiouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Thiouridine?
Yes, KEHONG BIO provides custom synthesis services for 2-Thiouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.