EGFR/HER2 Inhibitor
TL;DR: EGFR/HER2 Inhibitor (CAS 202272-68-2) is a chemical compound with molecular formula C23H21N7 and molecular weight 395.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
Also Known As: EGFR/HER2 Inhibitor, Lopac-G-0668, Lopac0_000509, GW282974X, GW2974A
| Molecular Formula | C23H21N7 |
|---|---|
| Molecular Weight | 395.19 g/mol |
| LogP | 4.2324 |
| Topological Polar Surface Area | 71.76 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 395.18585 |
| Heavy Atoms | 30 |
| Complexity | 1325.75 |
Chemical Identifiers
| CAS Number | 202272-68-2 |
|---|---|
| SMILES | CN(C)C1=NC=C2C(=C1)C(=NC=N2)NC3=CC4=C(C=C3)N(N=C4)CC5=CC=CC=C5 |
Product Overview
EGFR/HER2 Inhibitor (CAS 202272-68-2), with molecular formula C23H21N7 and molecular weight 395.19 g/mol. IUPAC: 4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine.
Chemical Property Profile of EGFR/HER2 Inhibitor
Property Insights of EGFR/HER2 Inhibitor
The XLogP value of 4.2324 indicates that EGFR/HER2 Inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.76 Ų falls within the moderate polarity range, balancing permeability and solubility for EGFR/HER2 Inhibitor. Following Lipinski's Rule of Five, EGFR/HER2 Inhibitor has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of EGFR/HER2 Inhibitor?
The CAS number of EGFR/HER2 Inhibitor is 202272-68-2.
What is the molecular formula of EGFR/HER2 Inhibitor?
The molecular formula of EGFR/HER2 Inhibitor is C23H21N7.
What is the molecular weight of EGFR/HER2 Inhibitor?
The molecular weight of EGFR/HER2 Inhibitor is 395.19 g/mol.
Where can I buy EGFR/HER2 Inhibitor?
You can request a quote for EGFR/HER2 Inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for EGFR/HER2 Inhibitor?
Yes, KEHONG BIO provides custom synthesis services for EGFR/HER2 Inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.