![(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol structure](/static/products/202/202267-16-1.png)
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol
概要：(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol（CAS 202267-16-1）是一种化学化合物，分子式为C22H25F3N6O3，分子量为478.19 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(1S,2R,3R,5R)-3-(hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]pyrrolidin-3-yl]amino]purin-9-yl]cyclopentane-1,2-diol
又称：(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol, (1S,2R,3R,5R)-3-(hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]pyrrolidin-3-yl]amino]purin-9-yl]cyclopentane-1,2-diol
| 分子式 | C22H25F3N6O3 |
|---|---|
| 分子量 | 478.19 g/mol |
| LogP | 1.811 |
| 拓扑极性表面积 | 119.56 Ų |
| 氢键供体数 | 4 |
| 氢键受体数 | 8 |
| 可旋转键数 | 5 |
| 精确质量 | 478.19403 |
| 重原子数 | 34 |
| 复杂度 | 1154.9877 |
化学标识符
| CAS 编号 | 202267-16-1 |
|---|---|
| SMILES | C1CN(C[C@H]1NC2=C3C(=NC=N2)N(C=N3)[C@@H]4C[C@@H]([C@H]([C@H]4O)O)CO)C5=CC=C(C=C5)C(F)(F)F |
产品概述
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol（CAS 202267-16-1），分子式为C22H25F3N6O3，分子量为478.19 g/mol。IUPAC名：(1S,2R,3R,5R)-3-(hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]pyrrolidin-3-yl]amino]purin-9-yl]cyclopentane-1,2-diol。
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol化学性质概览
属性洞察：(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的XLogP值为1.811，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为119.56 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol有4个氢键供体和8个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的CAS号是多少？
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的CAS号为202267-16-1。
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的分子式是什么？
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的分子式为C22H25F3N6O3。
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的分子量是多少？
(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的分子量为478.19 g/mol。
在哪里可以购买(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol？
您可以直接向科弘生物询价(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol的定制合成服务？
是的，科弘生物提供(1S,2R,3R,5R)-3-(Hydroxymethyl)-5-[6-[[(3S)-1-[4-(trifluoromethyl)phenyl]-3-pyrrolidinyl]amino]-9H-purin-9-yl]-1,2-cyclopentanediol及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。