Tenofovir Disoproxil Fumarate
TL;DR: Tenofovir Disoproxil Fumarate (CAS 202138-50-9) is a chemical compound with molecular formula C23H34N5O14P and molecular weight 635.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;but-2-enedioic acid
Also Known As: Tenofovir Disoproxil Fumarate
| Molecular Formula | C23H34N5O14P |
|---|---|
| Molecular Weight | 635.18 g/mol |
| LogP | 2.7474 |
| Topological Polar Surface Area | 260.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 18 |
| Rotatable Bonds | 19 |
| Exact Mass | 635.18396 |
| Heavy Atoms | 43 |
| Complexity | 817.0 |
Chemical Identifiers
| CAS Number | 202138-50-9 |
|---|---|
| SMILES | C[C@@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C(=CC(=O)O)C(=O)O |
| InChIKey | VCMJCVGFSROFHV-UQKRIMTDSA-N |
Product Overview
Tenofovir Disoproxil Fumarate (CAS 202138-50-9), with molecular formula C23H34N5O14P and molecular weight 635.18 g/mol. IUPAC: [[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;but-2-enedioic acid.
Chemical Property Profile of Tenofovir Disoproxil Fumarate
Property Insights of Tenofovir Disoproxil Fumarate
The XLogP value of 2.7474 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tenofovir Disoproxil Fumarate. The TPSA of 260.0 Ų indicates high polarity, suggesting Tenofovir Disoproxil Fumarate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tenofovir Disoproxil Fumarate has 3 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tenofovir Disoproxil Fumarate?
The CAS number of Tenofovir Disoproxil Fumarate is 202138-50-9.
What is the molecular formula of Tenofovir Disoproxil Fumarate?
The molecular formula of Tenofovir Disoproxil Fumarate is C23H34N5O14P.
What is the molecular weight of Tenofovir Disoproxil Fumarate?
The molecular weight of Tenofovir Disoproxil Fumarate is 635.18 g/mol.
Where can I buy Tenofovir Disoproxil Fumarate?
You can request a quote for Tenofovir Disoproxil Fumarate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tenofovir Disoproxil Fumarate?
Yes, KEHONG BIO provides custom synthesis services for Tenofovir Disoproxil Fumarate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.