Clevidipine, (R)-
TL;DR: Clevidipine, (R)- (CAS 2018-89-5) is a chemical compound with molecular formula C21H23Cl2NO6 and molecular weight 455.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-(butanoyloxymethyl) 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Clevidipine, Clevidipine butyrate, Clevidipine, (R)-, (-)-R-Clevidipine, Cleviprex (TN)
| Molecular Formula | C21H23Cl2NO6 |
|---|---|
| Molecular Weight | 455.09 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 90.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 10 |
| Exact Mass | 455.09024 |
| Heavy Atoms | 30 |
| Complexity | 748.0 |
Chemical Identifiers
| CAS Number | 2018-89-5 |
|---|---|
| SMILES | CCCC(=O)OCOC(=O)C1=C(NC(=C([C@H]1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C |
| InChIKey | KPBZROQVTHLCDU-GOSISDBHSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Clevidipine, (R)- (CAS 2018-89-5), with molecular formula C21H23Cl2NO6 and molecular weight 455.09 g/mol. IUPAC: 5-O-(butanoyloxymethyl) 3-O-methyl (4R)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Clevidipine, (R)-
Property Insights of Clevidipine, (R)-
The XLogP value of 4.3 indicates that Clevidipine, (R)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Clevidipine, (R)-. Following Lipinski's Rule of Five, Clevidipine, (R)- has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clevidipine, (R)-?
The CAS number of Clevidipine, (R)- is 2018-89-5.
What is the molecular formula of Clevidipine, (R)-?
The molecular formula of Clevidipine, (R)- is C21H23Cl2NO6.
What is the molecular weight of Clevidipine, (R)-?
The molecular weight of Clevidipine, (R)- is 455.09 g/mol.
Where can I buy Clevidipine, (R)-?
You can request a quote for Clevidipine, (R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clevidipine, (R)-?
Yes, KEHONG BIO provides custom synthesis services for Clevidipine, (R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.