Tenofovir prodrug
TL;DR: Tenofovir prodrug (CAS 201341-07-3) is a chemical compound with molecular formula C23H38N5O10P and molecular weight 575.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(pentan-3-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl pentan-3-yl carbonate
Also Known As: Tenofovir prodrug, PMPA prodrug, Bis(3-PentylOC)PMPA, 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-((2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, bis(1-ethylpropyl) ester, 5-oxide, (R)-, [[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(1-ethylpropoxycarbonyloxymethoxy)phosphoryl]oxymethyl 1-ethylpropyl carbonate
| Molecular Formula | C23H38N5O10P |
|---|---|
| Molecular Weight | 575.24 g/mol |
| LogP | 4.596 |
| Topological Polar Surface Area | 185.44 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 17 |
| Exact Mass | 575.23566 |
| Heavy Atoms | 39 |
| Complexity | 1056.4326 |
Chemical Identifiers
| CAS Number | 201341-07-3 |
|---|---|
| SMILES | CCC(CC)OC(=O)OCOP(=O)(CO[C@H](C)CN1C=NC2=C(N=CN=C21)N)OCOC(=O)OC(CC)CC |
Product Overview
Tenofovir prodrug (CAS 201341-07-3), with molecular formula C23H38N5O10P and molecular weight 575.24 g/mol. IUPAC: [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(pentan-3-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl pentan-3-yl carbonate.
Chemical Property Profile of Tenofovir prodrug
Property Insights of Tenofovir prodrug
The XLogP value of 4.596 indicates that Tenofovir prodrug is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 185.44 Ų indicates high polarity, suggesting Tenofovir prodrug may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tenofovir prodrug has 1 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tenofovir prodrug?
The CAS number of Tenofovir prodrug is 201341-07-3.
What is the molecular formula of Tenofovir prodrug?
The molecular formula of Tenofovir prodrug is C23H38N5O10P.
What is the molecular weight of Tenofovir prodrug?
The molecular weight of Tenofovir prodrug is 575.24 g/mol.
Where can I buy Tenofovir prodrug?
You can request a quote for Tenofovir prodrug directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tenofovir prodrug?
Yes, KEHONG BIO provides custom synthesis services for Tenofovir prodrug and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.