替诺福韦酯
TL;DR: 替诺福韦酯 (CAS 201341-05-1) is a chemical compound with molecular formula C19H30N5O10P and molecular weight 519.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
替诺福韦酯
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate
Also Known As: Tenofovir disoproxil, PMPA prodrug, Bis(POC)PMPA, Viread, Tenofovir
| Molecular Formula | C19H30N5O10P |
|---|---|
| Molecular Weight | 519.17 g/mol |
| LogP | 3.0356 |
| Topological Polar Surface Area | 185.44 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 13 |
| Exact Mass | 519.17303 |
| Heavy Atoms | 35 |
| Complexity | 998.6174 |
Chemical Identifiers
| CAS Number | 201341-05-1 |
|---|---|
| SMILES | C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C |
Product Overview
替诺福韦酯 (CAS 201341-05-1), with molecular formula C19H30N5O10P and molecular weight 519.17 g/mol. IUPAC: [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate.
Chemical Property Profile of 替诺福韦酯
Property Insights of 替诺福韦酯
The XLogP value of 3.0356 indicates that 替诺福韦酯 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 185.44 Ų indicates high polarity, suggesting 替诺福韦酯 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 替诺福韦酯 has 1 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 替诺福韦酯?
The CAS number of 替诺福韦酯 is 201341-05-1.
What is the molecular formula of 替诺福韦酯?
The molecular formula of 替诺福韦酯 is C19H30N5O10P.
What is the molecular weight of 替诺福韦酯?
The molecular weight of 替诺福韦酯 is 519.17 g/mol.
Where can I buy 替诺福韦酯?
You can request a quote for 替诺福韦酯 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 替诺福韦酯?
Yes, KEHONG BIO provides custom synthesis services for 替诺福韦酯 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.