PMPA prodrug
TL;DR: PMPA prodrug (CAS 201340-99-0) is a chemical compound with molecular formula C21H34N5O10P and molecular weight 547.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(2-methylpropoxycarbonyloxymethoxy)phosphoryl]oxymethyl 2-methylpropyl carbonate
Also Known As: PMPA prodrug, Bis(IsobutylOC)PMPA, Tenofovir prodrug, 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-((2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, bis(2-methylpropyl) ester, 5-oxide, (R)-, [[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(isobutoxycarbonyloxymethoxy)phosphoryl]oxymethyl isobutyl carbonate
| Molecular Formula | C21H34N5O10P |
|---|---|
| Molecular Weight | 547.20 g/mol |
| LogP | 3.5308 |
| Topological Polar Surface Area | 185.44 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 15 |
| Exact Mass | 547.20435 |
| Heavy Atoms | 37 |
| Complexity | 1029.515 |
Chemical Identifiers
| CAS Number | 201340-99-0 |
|---|---|
| SMILES | C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OCC(C)C)OCOC(=O)OCC(C)C |
Product Overview
PMPA prodrug (CAS 201340-99-0), with molecular formula C21H34N5O10P and molecular weight 547.20 g/mol. IUPAC: [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(2-methylpropoxycarbonyloxymethoxy)phosphoryl]oxymethyl 2-methylpropyl carbonate.
Chemical Property Profile of PMPA prodrug
Property Insights of PMPA prodrug
The XLogP value of 3.5308 indicates that PMPA prodrug is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 185.44 Ų indicates high polarity, suggesting PMPA prodrug may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, PMPA prodrug has 1 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of PMPA prodrug?
The CAS number of PMPA prodrug is 201340-99-0.
What is the molecular formula of PMPA prodrug?
The molecular formula of PMPA prodrug is C21H34N5O10P.
What is the molecular weight of PMPA prodrug?
The molecular weight of PMPA prodrug is 547.20 g/mol.
Where can I buy PMPA prodrug?
You can request a quote for PMPA prodrug directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for PMPA prodrug?
Yes, KEHONG BIO provides custom synthesis services for PMPA prodrug and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.