Bis(EthylOC)PMPA
TL;DR: Bis(EthylOC)PMPA (CAS 201340-95-6) is a chemical compound with molecular formula C17H26N5O10P and molecular weight 491.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(ethoxycarbonyloxymethoxy)phosphoryl]oxymethyl ethyl carbonate
Also Known As: Bis(EthylOC)PMPA, Tenofovir prodrug, PMPA prodrug, 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-((2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, diethyl ester, 5-oxide, (R)-, [[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(ethoxycarbonyloxymethoxy)phosphoryl]oxymethyl ethyl carbonate
| Molecular Formula | C17H26N5O10P |
|---|---|
| Molecular Weight | 491.14 g/mol |
| LogP | 2.2586 |
| Topological Polar Surface Area | 185.44 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 13 |
| Exact Mass | 491.14172 |
| Heavy Atoms | 33 |
| Complexity | 942.81067 |
Chemical Identifiers
| CAS Number | 201340-95-6 |
|---|---|
| SMILES | CCOC(=O)OCOP(=O)(CO[C@H](C)CN1C=NC2=C(N=CN=C21)N)OCOC(=O)OCC |
Product Overview
Bis(EthylOC)PMPA (CAS 201340-95-6), with molecular formula C17H26N5O10P and molecular weight 491.14 g/mol. IUPAC: [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(ethoxycarbonyloxymethoxy)phosphoryl]oxymethyl ethyl carbonate.
Chemical Property Profile of Bis(EthylOC)PMPA
Property Insights of Bis(EthylOC)PMPA
The XLogP value of 2.2586 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bis(EthylOC)PMPA. The TPSA of 185.44 Ų indicates high polarity, suggesting Bis(EthylOC)PMPA may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bis(EthylOC)PMPA has 1 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bis(EthylOC)PMPA?
The CAS number of Bis(EthylOC)PMPA is 201340-95-6.
What is the molecular formula of Bis(EthylOC)PMPA?
The molecular formula of Bis(EthylOC)PMPA is C17H26N5O10P.
What is the molecular weight of Bis(EthylOC)PMPA?
The molecular weight of Bis(EthylOC)PMPA is 491.14 g/mol.
Where can I buy Bis(EthylOC)PMPA?
You can request a quote for Bis(EthylOC)PMPA directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bis(EthylOC)PMPA?
Yes, KEHONG BIO provides custom synthesis services for Bis(EthylOC)PMPA and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.