4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate structure

4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate

TL;DR: 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate (CAS 199864-88-5) is a chemical compound with molecular formula C21H20FN3O4 and molecular weight 397.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(Z)-but-2-enedioic acid;4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine

Also Known As: RS-127445 maleate, 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate, 0270AB, EX-A14721, (Z)-but-2-enedioic acid;4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine

CAS: 199864-88-5
Molecular Formula C21H20FN3O4
Molecular Weight 397.14 g/mol
LogP 3.8533
Topological Polar Surface Area 126.4 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 397.1438
Heavy Atoms 29
Complexity 1064.7094

Chemical Identifiers

CAS Number 199864-88-5
SMILES CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.C(=C\C(=O)O)\C(=O)O

Product Overview

4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate (CAS 199864-88-5), with molecular formula C21H20FN3O4 and molecular weight 397.14 g/mol. IUPAC: (Z)-but-2-enedioic acid;4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate

XLogP
3.8533
TPSA (Topological Polar Surface Area)
126.4
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
29
Complexity
1064.7094
Exact Mass
397.1438
Monoisotopic Mass
397.1438
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate

The XLogP value of 3.8533 indicates that 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 126.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate. Following Lipinski's Rule of Five, 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate?

The CAS number of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate is 199864-88-5.

What is the molecular formula of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate?

The molecular formula of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate is C21H20FN3O4.

What is the molecular weight of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate?

The molecular weight of 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate is 397.14 g/mol.

Where can I buy 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate?

You can request a quote for 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate?

Yes, KEHONG BIO provides custom synthesis services for 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine maleate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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