RS-127445 Hydrochloride
TL;DR: RS-127445 Hydrochloride (CAS 199864-87-4) is a chemical compound with molecular formula C17H17ClFN3 and molecular weight 317.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine;hydrochloride
Also Known As: RS-127445 hydrochloride, RS 127445 hydrochloride, 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine hydrochloride, MT500 Hydrochloride, rs127445 hydrochloride
| Molecular Formula | C17H17ClFN3 |
|---|---|
| Molecular Weight | 317.11 g/mol |
| LogP | 4.5633 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 317.1095 |
| Heavy Atoms | 22 |
| Complexity | 818.1083 |
Chemical Identifiers
| CAS Number | 199864-87-4 |
|---|---|
| SMILES | CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.Cl |
Product Overview
RS-127445 Hydrochloride (CAS 199864-87-4), with molecular formula C17H17ClFN3 and molecular weight 317.11 g/mol. IUPAC: 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine;hydrochloride.
Chemical Property Profile of RS-127445 Hydrochloride
Property Insights of RS-127445 Hydrochloride
The XLogP value of 4.5633 indicates that RS-127445 Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, RS-127445 Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RS-127445 Hydrochloride has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RS-127445 Hydrochloride?
The CAS number of RS-127445 Hydrochloride is 199864-87-4.
What is the molecular formula of RS-127445 Hydrochloride?
The molecular formula of RS-127445 Hydrochloride is C17H17ClFN3.
What is the molecular weight of RS-127445 Hydrochloride?
The molecular weight of RS-127445 Hydrochloride is 317.11 g/mol.
Where can I buy RS-127445 Hydrochloride?
You can request a quote for RS-127445 Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RS-127445 Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for RS-127445 Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.