Revaprazan structure

Revaprazan

TL;DR: Revaprazan (CAS 199463-33-7) is a chemical compound with molecular formula C22H23FN4 and molecular weight 362.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine

Also Known As: Revaprazan, Revanex, Revaprazan [INN], Revaprazan HCl, REVAPRAZANUM

CAS: 199463-33-7
Molecular Formula C22H23FN4
Molecular Weight 362.19 g/mol
LogP 5.3
Topological Polar Surface Area 41.1 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 362.19067
Heavy Atoms 27
Complexity 481.0

Chemical Identifiers

CAS Number 199463-33-7
SMILES CC1C2=CC=CC=C2CCN1C3=NC(=NC(=C3C)C)NC4=CC=C(C=C4)F
InChIKey LECZXZOBEZITCL-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (29 patents) Organic Building Blocks (2 patents) Pharmaceutical Intermediates (8 patents)

Product Overview

Revaprazan (CAS 199463-33-7), with molecular formula C22H23FN4 and molecular weight 362.19 g/mol. IUPAC: N-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Revaprazan

XLogP
5.3
TPSA (Topological Polar Surface Area)
41.1
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
27
Complexity
481.0
Exact Mass
362.19067
Monoisotopic Mass
362.19067
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Revaprazan

The XLogP value of 5.3 indicates that Revaprazan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.1 Ų, Revaprazan exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Revaprazan has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Revaprazan?

The CAS number of Revaprazan is 199463-33-7.

What is the molecular formula of Revaprazan?

The molecular formula of Revaprazan is C22H23FN4.

What is the molecular weight of Revaprazan?

The molecular weight of Revaprazan is 362.19 g/mol.

Where can I buy Revaprazan?

You can request a quote for Revaprazan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Revaprazan?

Yes, KEHONG BIO provides custom synthesis services for Revaprazan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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