4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine
TL;DR: 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine (CAS 199463-20-2) is a chemical compound with molecular formula C12H11ClFN3 and molecular weight 251.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine
Also Known As: 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine, 2-Pyrimidinamine, 4-chloro-N-(4-fluorophenyl)-5,6-dimethyl-, 4-chloro-2-(4-fluorophenylamino)-5,6-dimethylpyrimidine, 4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine, 4-chloro-N-(4-fluorophenyl)-5,6-dimethyl-2-Pyrimidinamine
| Molecular Formula | C12H11ClFN3 |
|---|---|
| Molecular Weight | 251.06 g/mol |
| LogP | 3.62954 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 251.06255 |
| Heavy Atoms | 17 |
| Complexity | 516.94214 |
Chemical Identifiers
| CAS Number | 199463-20-2 |
|---|---|
| SMILES | CC1=C(N=C(N=C1Cl)NC2=CC=C(C=C2)F)C |
Product Overview
4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine (CAS 199463-20-2), with molecular formula C12H11ClFN3 and molecular weight 251.06 g/mol. IUPAC: 4-chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine.
Chemical Property Profile of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine
Property Insights of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine
The XLogP value of 3.62954 indicates that 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.81 Ų, 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine?
The CAS number of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine is 199463-20-2.
What is the molecular formula of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine?
The molecular formula of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine is C12H11ClFN3.
What is the molecular weight of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine?
The molecular weight of 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine is 251.06 g/mol.
Where can I buy 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine?
You can request a quote for 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.