L-375378
TL;DR: L-375378 (CAS 199294-70-7) is a chemical compound with molecular formula C22H26N6O2 and molecular weight 406.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(6-amino-2-methyl-3-pyridinyl)methyl]-2-[6-methyl-2-oxo-3-(2-phenylethylamino)pyrazin-1-yl]acetamide
Also Known As: L-375378 free base, L-375378, J1.059.018C, L-37378, L 375378
| Molecular Formula | C22H26N6O2 |
|---|---|
| Molecular Weight | 406.21 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 406.21173 |
| Heavy Atoms | 30 |
| Complexity | 671.0 |
Chemical Identifiers
| CAS Number | 199294-70-7 |
|---|---|
| SMILES | CC1=CN=C(C(=O)N1CC(=O)NCC2=C(N=C(C=C2)N)C)NCCC3=CC=CC=C3 |
| InChIKey | PVDHYBJORRALSQ-UHFFFAOYSA-N |
Product Overview
L-375378 (CAS 199294-70-7), with molecular formula C22H26N6O2 and molecular weight 406.21 g/mol. IUPAC: N-[(6-amino-2-methyl-3-pyridinyl)methyl]-2-[6-methyl-2-oxo-3-(2-phenylethylamino)pyrazin-1-yl]acetamide.
Chemical Property Profile of L-375378
Property Insights of L-375378
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for L-375378. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for L-375378. Following Lipinski's Rule of Five, L-375378 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-375378?
The CAS number of L-375378 is 199294-70-7.
What is the molecular formula of L-375378?
The molecular formula of L-375378 is C22H26N6O2.
What is the molecular weight of L-375378?
The molecular weight of L-375378 is 406.21 g/mol.
Where can I buy L-375378?
You can request a quote for L-375378 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-375378?
Yes, KEHONG BIO provides custom synthesis services for L-375378 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.