(2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one
TL;DR: (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one (CAS 19872-86-7) is a chemical compound with molecular formula C14H8ClNO2 and molecular weight 257.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2E)-5-chloro-2-(pyridin-2-ylmethylidene)-1-benzofuran-3-one
Also Known As: 5-chloro-2-(pyridin-2-ylmethylidene)benzofuran-3-one, (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one, (2E)-5-chloro-2-(pyridin-2-ylmethylidene)-1-benzofuran-3-one
| Molecular Formula | C14H8ClNO2 |
|---|---|
| Molecular Weight | 257.02 g/mol |
| LogP | 3.3512 |
| Topological Polar Surface Area | 39.19 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 257.02435 |
| Heavy Atoms | 18 |
| Complexity | 650.0985 |
Chemical Identifiers
| CAS Number | 19872-86-7 |
|---|---|
| SMILES | C1=CC=NC(=C1)/C=C/2\C(=O)C3=C(O2)C=CC(=C3)Cl |
Product Overview
(2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one (CAS 19872-86-7), with molecular formula C14H8ClNO2 and molecular weight 257.02 g/mol. IUPAC: (2E)-5-chloro-2-(pyridin-2-ylmethylidene)-1-benzofuran-3-one.
Chemical Property Profile of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one
Property Insights of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one
The XLogP value of 3.3512 indicates that (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.19 Ų, (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one?
The CAS number of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one is 19872-86-7.
What is the molecular formula of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one?
The molecular formula of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one is C14H8ClNO2.
What is the molecular weight of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one?
The molecular weight of (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one is 257.02 g/mol.
Where can I buy (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one?
You can request a quote for (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one?
Yes, KEHONG BIO provides custom synthesis services for (2E)-5-Chloro-2-(pyridin-2-ylmethylidene)-2,3-dihydro-1-benzofuran-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.