Epothilone G1
TL;DR: Epothilone G1 (CAS 198570-99-9) is a chemical compound with molecular formula C26H39NO7 and molecular weight 477.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
Also Known As: epothilone G1, (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo(14.1.0)heptadecane-5,9-dione, RefChem:137345
| Molecular Formula | C26H39NO7 |
|---|---|
| Molecular Weight | 477.27 g/mol |
| LogP | 3.61892 |
| Topological Polar Surface Area | 122.39 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 477.27264 |
| Heavy Atoms | 34 |
| Complexity | 904.7154 |
Chemical Identifiers
| CAS Number | 198570-99-9 |
|---|---|
| SMILES | C[C@H]1CCC[C@@H]2[C@@H](O2)C[C@H](OC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=COC(=N3)C)/C |
Product Overview
Epothilone G1 (CAS 198570-99-9), with molecular formula C26H39NO7 and molecular weight 477.27 g/mol. IUPAC: (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-oxazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione.
Chemical Property Profile of Epothilone G1
Property Insights of Epothilone G1
The XLogP value of 3.61892 indicates that Epothilone G1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.39 Ų falls within the moderate polarity range, balancing permeability and solubility for Epothilone G1. Following Lipinski's Rule of Five, Epothilone G1 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Epothilone G1?
The CAS number of Epothilone G1 is 198570-99-9.
What is the molecular formula of Epothilone G1?
The molecular formula of Epothilone G1 is C26H39NO7.
What is the molecular weight of Epothilone G1?
The molecular weight of Epothilone G1 is 477.27 g/mol.
Where can I buy Epothilone G1?
You can request a quote for Epothilone G1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Epothilone G1?
Yes, KEHONG BIO provides custom synthesis services for Epothilone G1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.