2-羟基去甲丙米嗪
TL;DR: 2-羟基去甲丙米嗪 (CAS 1977-15-7) is a chemical compound with molecular formula C18H22N2O and molecular weight 282.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-羟基去甲丙米嗪
11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol
Also Known As: 2-Hydroxydesipramine, 2-Hydroxy Desipramine, 2-hydroxy-desipramine, 2-Hydroxydesmethylimipramine, 2-OH-DMI
| Molecular Formula | C18H22N2O |
|---|---|
| Molecular Weight | 282.17 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 35.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 282.17322 |
| Heavy Atoms | 21 |
| Complexity | 322.0 |
Chemical Identifiers
| CAS Number | 1977-15-7 |
|---|---|
| SMILES | CNCCCN1C2=C(CCC3=CC=CC=C31)C=C(C=C2)O |
| InChIKey | NVJBOLMRGMDGLD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-羟基去甲丙米嗪 (CAS 1977-15-7), with molecular formula C18H22N2O and molecular weight 282.17 g/mol. IUPAC: 11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol.
Chemical Property Profile of 2-羟基去甲丙米嗪
Property Insights of 2-羟基去甲丙米嗪
The XLogP value of 4.5 indicates that 2-羟基去甲丙米嗪 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.5 Ų, 2-羟基去甲丙米嗪 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-羟基去甲丙米嗪 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-羟基去甲丙米嗪?
The CAS number of 2-羟基去甲丙米嗪 is 1977-15-7.
What is the molecular formula of 2-羟基去甲丙米嗪?
The molecular formula of 2-羟基去甲丙米嗪 is C18H22N2O.
What is the molecular weight of 2-羟基去甲丙米嗪?
The molecular weight of 2-羟基去甲丙米嗪 is 282.17 g/mol.
Where can I buy 2-羟基去甲丙米嗪?
You can request a quote for 2-羟基去甲丙米嗪 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-羟基去甲丙米嗪?
Yes, KEHONG BIO provides custom synthesis services for 2-羟基去甲丙米嗪 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.