Protoberberine structure

Protoberberine

TL;DR: Protoberberine (CAS 19716-69-9) is a chemical compound with molecular formula C17H14N+ and molecular weight 232.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium

Also Known As: Protoberberine, protoberberine iodide, protoberberine hydroxide, 5,6-Dihydrodibenzo(a,g)quinolizinium, 5,6-dihydrodibenzo[a,g]quinolizinium

CAS: 19716-69-9
Molecular Formula C17H14N+
Molecular Weight 232.11 g/mol
LogP 3.9
Topological Polar Surface Area 3.9 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 0
Rotatable Bonds 0
Exact Mass 232.11263
Heavy Atoms 18
Complexity 300.0

Chemical Identifiers

CAS Number 19716-69-9
SMILES C1C[N+]2=CC3=CC=CC=C3C=C2C4=CC=CC=C41
InChIKey UICBHOXXGLYZJH-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (22 patents) Pharmaceutical Intermediates (10 patents)

Product Overview

Protoberberine (CAS 19716-69-9), with molecular formula C17H14N+ and molecular weight 232.11 g/mol. IUPAC: 5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Protoberberine

XLogP
3.9
TPSA (Topological Polar Surface Area)
3.9
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
0
Rotatable Bonds
0
Heavy Atoms
18
Complexity
300.0
Exact Mass
232.11263
Monoisotopic Mass
232.11263
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Protoberberine

The XLogP value of 3.9 indicates that Protoberberine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.9 Ų, Protoberberine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Protoberberine has 0 hydrogen bond donor(s) and 0 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Protoberberine?

The CAS number of Protoberberine is 19716-69-9.

What is the molecular formula of Protoberberine?

The molecular formula of Protoberberine is C17H14N+.

What is the molecular weight of Protoberberine?

The molecular weight of Protoberberine is 232.11 g/mol.

Where can I buy Protoberberine?

You can request a quote for Protoberberine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Protoberberine?

Yes, KEHONG BIO provides custom synthesis services for Protoberberine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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