8-Methyl-6-chloroisoquinoline structure

8-Methyl-6-chloroisoquinoline

TL;DR: 8-Methyl-6-chloroisoquinoline (CAS 196875-78-2) is a chemical compound with molecular formula C10H8ClN and molecular weight 177.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-chloro-8-methylisoquinoline

Also Known As: 6-chloro-8-methylisoquinoline, 8-methyl-6-chloroisoquinoline, 6-chloro-8-methyl-isoquinoline, Isoquinoline, 6-chloro-8-methyl-, 834-215-3

CAS: 196875-78-2
Molecular Formula C10H8ClN
Molecular Weight 177.03 g/mol
LogP 3.19662
Topological Polar Surface Area 12.89 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 0
Exact Mass 177.03453
Heavy Atoms 12
Complexity 423.10812

Chemical Identifiers

CAS Number 196875-78-2
SMILES CC1=CC(=CC2=C1C=NC=C2)Cl

Product Overview

8-Methyl-6-chloroisoquinoline (CAS 196875-78-2), with molecular formula C10H8ClN and molecular weight 177.03 g/mol. IUPAC: 6-chloro-8-methylisoquinoline.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 8-Methyl-6-chloroisoquinoline

XLogP
3.19662
TPSA (Topological Polar Surface Area)
12.89
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
0
Heavy Atoms
12
Complexity
423.10812
Exact Mass
177.03453
Monoisotopic Mass
177.03453
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8-Methyl-6-chloroisoquinoline

The XLogP value of 3.19662 indicates that 8-Methyl-6-chloroisoquinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.89 Ų, 8-Methyl-6-chloroisoquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Methyl-6-chloroisoquinoline has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8-Methyl-6-chloroisoquinoline?

The CAS number of 8-Methyl-6-chloroisoquinoline is 196875-78-2.

What is the molecular formula of 8-Methyl-6-chloroisoquinoline?

The molecular formula of 8-Methyl-6-chloroisoquinoline is C10H8ClN.

What is the molecular weight of 8-Methyl-6-chloroisoquinoline?

The molecular weight of 8-Methyl-6-chloroisoquinoline is 177.03 g/mol.

Where can I buy 8-Methyl-6-chloroisoquinoline?

You can request a quote for 8-Methyl-6-chloroisoquinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8-Methyl-6-chloroisoquinoline?

Yes, KEHONG BIO provides custom synthesis services for 8-Methyl-6-chloroisoquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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