1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea
TL;DR: 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea (CAS 196875-41-9) is a chemical compound with molecular formula C17H14ClN3OS and molecular weight 343.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-chloro-7-methoxyquinolin-2-yl)-3-phenylthiourea
Also Known As: NCIStruc1_001647, NCIStruc2_001387, NCI60_002763, 1-(4-chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea, 1-(4-chloro-7-methoxyquinolin-2-yl)-3-phenylthiourea
| Molecular Formula | C17H14ClN3OS |
|---|---|
| Molecular Weight | 343.05 g/mol |
| LogP | 4.7057 |
| Topological Polar Surface Area | 46.18 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 343.0546 |
| Heavy Atoms | 23 |
| Complexity | 855.08636 |
Chemical Identifiers
| CAS Number | 196875-41-9 |
|---|---|
| SMILES | COC1=CC2=C(C=C1)C(=CC(=N2)NC(=S)NC3=CC=CC=C3)Cl |
Product Overview
1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea (CAS 196875-41-9), with molecular formula C17H14ClN3OS and molecular weight 343.05 g/mol. IUPAC: 1-(4-chloro-7-methoxyquinolin-2-yl)-3-phenylthiourea.
Chemical Property Profile of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea
Property Insights of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea
The XLogP value of 4.7057 indicates that 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.18 Ų, 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea?
The CAS number of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea is 196875-41-9.
What is the molecular formula of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea?
The molecular formula of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea is C17H14ClN3OS.
What is the molecular weight of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea?
The molecular weight of 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea is 343.05 g/mol.
Where can I buy 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea?
You can request a quote for 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-Chloro-7-methoxy-2-quinolyl)-3-phenyl-2-thiourea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.