10-羟基喜树碱
TL;DR: 10-羟基喜树碱 (CAS 19685-09-7) is a chemical compound with molecular formula C20H16N2O5 and molecular weight 364.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-羟基喜树碱
(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Also Known As: 10-Hydroxycamptothecin, (S)-10-Hydroxycamptothecin, Hydroxycamptothecin, 10-hydroxycamptothecine, Hydroxycamptothecine
| Molecular Formula | C20H16N2O5 |
|---|---|
| Molecular Weight | 364.11 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 100.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 364.10593 |
| Heavy Atoms | 27 |
| Complexity | 774.0 |
Chemical Identifiers
| CAS Number | 19685-09-7 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O |
| InChIKey | HAWSQZCWOQZXHI-FQEVSTJZSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
10-羟基喜树碱 (CAS 19685-09-7), with molecular formula C20H16N2O5 and molecular weight 364.11 g/mol. IUPAC: (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 10-羟基喜树碱
Property Insights of 10-羟基喜树碱
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-羟基喜树碱. The TPSA of 100.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 10-羟基喜树碱. Following Lipinski's Rule of Five, 10-羟基喜树碱 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-羟基喜树碱?
The CAS number of 10-羟基喜树碱 is 19685-09-7.
What is the molecular formula of 10-羟基喜树碱?
The molecular formula of 10-羟基喜树碱 is C20H16N2O5.
What is the molecular weight of 10-羟基喜树碱?
The molecular weight of 10-羟基喜树碱 is 364.11 g/mol.
Where can I buy 10-羟基喜树碱?
You can request a quote for 10-羟基喜树碱 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-羟基喜树碱?
Yes, KEHONG BIO provides custom synthesis services for 10-羟基喜树碱 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.