(8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol
TL;DR: (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol (CAS 19669-82-0) is a chemical compound with molecular formula C18H24O2 and molecular weight 272.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Also Known As: Isoestradiol, 8-Epiestradiol, Isoestrone, DL-8-Isoestradiol, estradiol
| Molecular Formula | C18H24O2 |
|---|---|
| Molecular Weight | 272.18 g/mol |
| LogP | 3.6092 |
| Topological Polar Surface Area | 40.46 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 272.17764 |
| Heavy Atoms | 20 |
| Complexity | 538.2198 |
Chemical Identifiers
| CAS Number | 19669-82-0 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O |
Product Overview
(8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol (CAS 19669-82-0), with molecular formula C18H24O2 and molecular weight 272.18 g/mol. IUPAC: (8S,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol.
Chemical Property Profile of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol
Property Insights of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol
The XLogP value of 3.6092 indicates that (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.46 Ų, (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol?
The CAS number of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol is 19669-82-0.
What is the molecular formula of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol?
The molecular formula of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol is C18H24O2.
What is the molecular weight of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol?
The molecular weight of (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol is 272.18 g/mol.
Where can I buy (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol?
You can request a quote for (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol?
Yes, KEHONG BIO provides custom synthesis services for (8alpha,17beta)-Estra-1,3,5(10)-triene-3,17-diol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.