塞马尼布
TL;DR: 塞马尼布 (CAS 194413-57-5) is a chemical compound with molecular formula C15H14N2O and molecular weight 238.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
塞马尼布
(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
Also Known As: Semaxanib, Semaxinib, Semoxind, Romiplostim, SU 5416
| Molecular Formula | C15H14N2O |
|---|---|
| Molecular Weight | 238.11 g/mol |
| LogP | 3.12424 |
| Topological Polar Surface Area | 44.89 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 238.11061 |
| Heavy Atoms | 18 |
| Complexity | 664.8832 |
Chemical Identifiers
| CAS Number | 194413-57-5 |
|---|---|
| SMILES | CC1=CC(=C(N1)/C=C\2/C3=CC=CC=C3NC2=O)C |
Product Overview
塞马尼布 (CAS 194413-57-5), with molecular formula C15H14N2O and molecular weight 238.11 g/mol. IUPAC: (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one.
Chemical Property Profile of 塞马尼布
Property Insights of 塞马尼布
The XLogP value of 3.12424 indicates that 塞马尼布 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.89 Ų, 塞马尼布 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 塞马尼布 has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 塞马尼布?
The CAS number of 塞马尼布 is 194413-57-5.
What is the molecular formula of 塞马尼布?
The molecular formula of 塞马尼布 is C15H14N2O.
What is the molecular weight of 塞马尼布?
The molecular weight of 塞马尼布 is 238.11 g/mol.
Where can I buy 塞马尼布?
You can request a quote for 塞马尼布 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 塞马尼布?
Yes, KEHONG BIO provides custom synthesis services for 塞马尼布 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.