Dexamethasone Pivalate structure

Dexamethasone Pivalate

TL;DR: Dexamethasone Pivalate (CAS 1926-94-9) is a chemical compound with molecular formula C27H37FO6 and molecular weight 476.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

Also Known As: Dexamethasone pivalate, Opticortenol, Dexamethasone 21-pivalate, Dexamethasone trimethyl acetate, dexamethasone21-pivalate

CAS: 1926-94-9
Molecular Formula C27H37FO6
Molecular Weight 476.26 g/mol
LogP 4.2
Topological Polar Surface Area 101.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 476.25742
Heavy Atoms 34
Complexity 994.0

Chemical Identifiers

CAS Number 1926-94-9
SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C(C)(C)C)O)C)O)F)C
InChIKey XMQRFWOHEPJZPS-JHUFMRCFSA-N

Product Overview

Dexamethasone Pivalate (CAS 1926-94-9), with molecular formula C27H37FO6 and molecular weight 476.26 g/mol. IUPAC: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dexamethasone Pivalate

XLogP
4.2
TPSA (Topological Polar Surface Area)
101.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
34
Complexity
994.0
Exact Mass
476.25742
Monoisotopic Mass
476.25742
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dexamethasone Pivalate

The XLogP value of 4.2 indicates that Dexamethasone Pivalate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Dexamethasone Pivalate. Following Lipinski's Rule of Five, Dexamethasone Pivalate has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dexamethasone Pivalate?

The CAS number of Dexamethasone Pivalate is 1926-94-9.

What is the molecular formula of Dexamethasone Pivalate?

The molecular formula of Dexamethasone Pivalate is C27H37FO6.

What is the molecular weight of Dexamethasone Pivalate?

The molecular weight of Dexamethasone Pivalate is 476.26 g/mol.

Where can I buy Dexamethasone Pivalate?

You can request a quote for Dexamethasone Pivalate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dexamethasone Pivalate?

Yes, KEHONG BIO provides custom synthesis services for Dexamethasone Pivalate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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