Thio-NADP structure

Thio-NADP

TL;DR: Thio-NADP (CAS 19254-05-8) is a chemical compound with molecular formula C21H28N7O16P3S and molecular weight 759.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2R,3R,4S,5R)-5-[[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-2-(3-carbamothioylpyridin-1-ium-1-yl)-4-hydroxyoxolan-3-olate

Also Known As: Thio-NADP, Thionicotinamide adenine dinucleotide phosphate, (2R,3R,4S,5R)-5-[[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-2-(3-carbamothioylpyridin-1-ium-1-yl)-4-hydroxyoxolan-3-olate, Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'-5'-ester with 3-(aminothioxomethyl)-1-beta-D-ribofuranosylpyridinium inner salt, ADENOSINE 5/'-(TRIHYDROGEN DIPHOSATE), 2/'-(SODIUM HYDROGEN PHOSPHATE), P/',5/'-ESTER WITH 3-(AMINOT

CAS: 19254-05-8
Molecular Formula C21H28N7O16P3S
Molecular Weight 759.05 g/mol
LogP -2.9956
Topological Polar Surface Area 350.55 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 17
Rotatable Bonds 13
Exact Mass 759.0526
Heavy Atoms 48
Complexity 1815.5599

Chemical Identifiers

CAS Number 19254-05-8
SMILES C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)[O-])C(=S)N

Product Overview

Thio-NADP (CAS 19254-05-8), with molecular formula C21H28N7O16P3S and molecular weight 759.05 g/mol. IUPAC: (2R,3R,4S,5R)-5-[[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-2-(3-carbamothioylpyridin-1-ium-1-yl)-4-hydroxyoxolan-3-olate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thio-NADP

XLogP
-2.9956
TPSA (Topological Polar Surface Area)
350.55
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
17
Rotatable Bonds
13
Heavy Atoms
48
Complexity
1815.5599
Exact Mass
759.0526
Monoisotopic Mass
759.0526
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thio-NADP

The XLogP value of -2.9956 indicates that Thio-NADP is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 350.55 Ų indicates high polarity, suggesting Thio-NADP may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thio-NADP has 8 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thio-NADP?

The CAS number of Thio-NADP is 19254-05-8.

What is the molecular formula of Thio-NADP?

The molecular formula of Thio-NADP is C21H28N7O16P3S.

What is the molecular weight of Thio-NADP?

The molecular weight of Thio-NADP is 759.05 g/mol.

Where can I buy Thio-NADP?

You can request a quote for Thio-NADP directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thio-NADP?

Yes, KEHONG BIO provides custom synthesis services for Thio-NADP and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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