Alfuzosin Impurity 1
TL;DR: Alfuzosin Impurity 1 (CAS 19216-68-3) is a chemical compound with molecular formula C12H17ClN4O2 and molecular weight 284.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,7-dimethoxy-2-N,2-N-dimethylquinazoline-2,4-diamine;hydrochloride
Also Known As: Alfuzosin Impurity 1, 6,7-dimethoxy-N,N-dimethyl-quinazoline-2,4-diamine, Alfuzosin hydrochloride EP Impurity F hydrochloride, 4-AMINO-6,7-DIMETHOXY-2-DIMETHYLAMINOQUINAZOLINE HYDROCHLORIDE, 6,7-dimethoxy-2-N,2-N-dimethylquinazoline-2,4-diamine;hydrochloride
| Molecular Formula | C12H17ClN4O2 |
|---|---|
| Molecular Weight | 284.10 g/mol |
| LogP | 1.717 |
| Topological Polar Surface Area | 73.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 284.104 |
| Heavy Atoms | 19 |
| Complexity | 589.44135 |
Chemical Identifiers
| CAS Number | 19216-68-3 |
|---|---|
| SMILES | CN(C)C1=NC2=CC(=C(C=C2C(=N1)N)OC)OC.Cl |
Product Overview
Alfuzosin Impurity 1 (CAS 19216-68-3), with molecular formula C12H17ClN4O2 and molecular weight 284.10 g/mol. IUPAC: 6,7-dimethoxy-2-N,2-N-dimethylquinazoline-2,4-diamine;hydrochloride.
Chemical Property Profile of Alfuzosin Impurity 1
Property Insights of Alfuzosin Impurity 1
The XLogP value of 1.717 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Alfuzosin Impurity 1. The TPSA of 73.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Alfuzosin Impurity 1. Following Lipinski's Rule of Five, Alfuzosin Impurity 1 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Alfuzosin Impurity 1?
The CAS number of Alfuzosin Impurity 1 is 19216-68-3.
What is the molecular formula of Alfuzosin Impurity 1?
The molecular formula of Alfuzosin Impurity 1 is C12H17ClN4O2.
What is the molecular weight of Alfuzosin Impurity 1?
The molecular weight of Alfuzosin Impurity 1 is 284.10 g/mol.
Where can I buy Alfuzosin Impurity 1?
You can request a quote for Alfuzosin Impurity 1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Alfuzosin Impurity 1?
Yes, KEHONG BIO provides custom synthesis services for Alfuzosin Impurity 1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.