![8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane structure](/static/products/1900/190012-29-4.webp)
8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane
TL;DR: 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane (CAS 190012-29-4) is a chemical compound with molecular formula C14H16FNO3 and molecular weight 265.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(4-fluorophenyl)methanone
Also Known As: 8-(4-fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane, 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(4-fluorophenyl)methanone, AS-871/42709350, (1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)(4-fluorophenyl)methanone, (4-fluorophenyl)(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone
| Molecular Formula | C14H16FNO3 |
|---|---|
| Molecular Weight | 265.11 g/mol |
| LogP | 1.8048 |
| Topological Polar Surface Area | 38.77 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 265.11142 |
| Heavy Atoms | 19 |
| Complexity | 458.08435 |
Chemical Identifiers
| CAS Number | 190012-29-4 |
|---|---|
| SMILES | C1CN(CCC12OCCO2)C(=O)C3=CC=C(C=C3)F |
Product Overview
8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane (CAS 190012-29-4), with molecular formula C14H16FNO3 and molecular weight 265.11 g/mol. IUPAC: 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(4-fluorophenyl)methanone.
Chemical Property Profile of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane
Property Insights of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane
The XLogP value of 1.8048 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane. With a topological polar surface area (TPSA) of 38.77 Ų, 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane?
The CAS number of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane is 190012-29-4.
What is the molecular formula of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane?
The molecular formula of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane is C14H16FNO3.
What is the molecular weight of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane?
The molecular weight of 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane is 265.11 g/mol.
Where can I buy 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane?
You can request a quote for 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane?
Yes, KEHONG BIO provides custom synthesis services for 8-(4-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.