troglitazone
TL;DR: troglitazone (CAS 189764-83-8) is a chemical compound with molecular formula C24H27NO5S and molecular weight 441.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5R)-5-[[4-[[(2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: troglitazone, Rezulin, 2qm9, (2R,5R)-Troglitazone, Troglitazone, (2R,5R)-(+/-)-
| Molecular Formula | C24H27NO5S |
|---|---|
| Molecular Weight | 441.16 g/mol |
| LogP | 4.37426 |
| Topological Polar Surface Area | 84.86 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 441.16098 |
| Heavy Atoms | 31 |
| Complexity | 1049.1705 |
Chemical Identifiers
| CAS Number | 189764-83-8 |
|---|---|
| SMILES | CC1=C(C2=C(CC[C@](O2)(C)COC3=CC=C(C=C3)C[C@@H]4C(=O)NC(=O)S4)C(=C1O)C)C |
Product Overview
troglitazone (CAS 189764-83-8), with molecular formula C24H27NO5S and molecular weight 441.16 g/mol. IUPAC: (5R)-5-[[4-[[(2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of troglitazone
Property Insights of troglitazone
The XLogP value of 4.37426 indicates that troglitazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.86 Ų falls within the moderate polarity range, balancing permeability and solubility for troglitazone. Following Lipinski's Rule of Five, troglitazone has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of troglitazone?
The CAS number of troglitazone is 189764-83-8.
What is the molecular formula of troglitazone?
The molecular formula of troglitazone is C24H27NO5S.
What is the molecular weight of troglitazone?
The molecular weight of troglitazone is 441.16 g/mol.
Where can I buy troglitazone?
You can request a quote for troglitazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for troglitazone?
Yes, KEHONG BIO provides custom synthesis services for troglitazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.