Motexafin structure

Motexafin

TL;DR: Motexafin (CAS 189752-49-6) is a chemical compound with molecular formula C48H67N5O10 and molecular weight 873.49 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[4,5-diethyl-24-(3-hydroxypropyl)-16,17-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-10,23-dimethyl-13,20,25,26,27-pentazapentacyclo[20.2.1.13,6.18,11.014,19]heptacosa-1(25),2,4,6(27),7,9,11,13,15,17,19,21,23-tridecaen-9-yl]propan-1-ol

Also Known As: Motexafin, Motexafin [INN], Motexafina, Motexafine, MOTEXAFIN [WHO-DD]

CAS: 189752-49-6
Molecular Formula C48H67N5O10
Molecular Weight 873.49 g/mol
LogP 3.1
Topological Polar Surface Area 176.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 15
Rotatable Bonds 28
Exact Mass 873.4888
Heavy Atoms 63
Complexity 2010.0

Chemical Identifiers

CAS Number 189752-49-6
SMILES CCC1=C(C2=NC1=CC3=NC(=CN=C4C=C(C(=CC4=NC=C5C(=C(C(=C2)N5)CCCO)C)OCCOCCOCCOC)OCCOCCOCCOC)C(=C3CCCO)C)CC
InChIKey JFOHFDSMPQIOES-UHFFFAOYSA-N

Product Overview

Motexafin (CAS 189752-49-6), with molecular formula C48H67N5O10 and molecular weight 873.49 g/mol. IUPAC: 3-[4,5-diethyl-24-(3-hydroxypropyl)-16,17-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-10,23-dimethyl-13,20,25,26,27-pentazapentacyclo[20.2.1.13,6.18,11.014,19]heptacosa-1(25),2,4,6(27),7,9,11,13,15,17,19,21,23-tridecaen-9-yl]propan-1-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Motexafin

XLogP
3.1
TPSA (Topological Polar Surface Area)
176.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
15
Rotatable Bonds
28
Heavy Atoms
63
Complexity
2010.0
Exact Mass
873.4888
Monoisotopic Mass
873.4888
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Motexafin

The XLogP value of 3.1 indicates that Motexafin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 176.0 Ų indicates high polarity, suggesting Motexafin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Motexafin has 3 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Motexafin?

The CAS number of Motexafin is 189752-49-6.

What is the molecular formula of Motexafin?

The molecular formula of Motexafin is C48H67N5O10.

What is the molecular weight of Motexafin?

The molecular weight of Motexafin is 873.49 g/mol.

Where can I buy Motexafin?

You can request a quote for Motexafin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Motexafin?

Yes, KEHONG BIO provides custom synthesis services for Motexafin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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