(R)-Nigaldipine hydrochloride
TL;DR: (R)-Nigaldipine hydrochloride (CAS 189624-85-9) is a chemical compound with molecular formula C41H44Cl2N4O6 and molecular weight 758.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-ethenyl 3-O-methyl (2S)-2-[4-(4-benzhydrylpiperazin-1-yl)phenyl]-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydro-1H-pyridine-3,5-dicarboxylate;dihydrochloride
Also Known As: (R)-Nigaldipine hydrochloride, Dexniguldipine hydrochloride, (-)-Nigaldipine hydrochloride, (S)-(+)-Watanidipine hydrochloride, BY 935
| Molecular Formula | C41H44Cl2N4O6 |
|---|---|
| Molecular Weight | 758.26 g/mol |
| LogP | 7.7021 |
| Topological Polar Surface Area | 114.25 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 758.2638 |
| Heavy Atoms | 53 |
| Complexity | 1895.544 |
Chemical Identifiers
| CAS Number | 189624-85-9 |
|---|---|
| SMILES | CC1=C(C(C([C@@](N1)(C)C2=CC=C(C=C2)N3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)OC)C6=CC(=CC=C6)[N+](=O)[O-])C(=O)OC=C.Cl.Cl |
Product Overview
(R)-Nigaldipine hydrochloride (CAS 189624-85-9), with molecular formula C41H44Cl2N4O6 and molecular weight 758.26 g/mol. IUPAC: 5-O-ethenyl 3-O-methyl (2S)-2-[4-(4-benzhydrylpiperazin-1-yl)phenyl]-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydro-1H-pyridine-3,5-dicarboxylate;dihydrochloride.
Chemical Property Profile of (R)-Nigaldipine hydrochloride
Property Insights of (R)-Nigaldipine hydrochloride
The XLogP value of 7.7021 indicates that (R)-Nigaldipine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.25 Ų falls within the moderate polarity range, balancing permeability and solubility for (R)-Nigaldipine hydrochloride. Following Lipinski's Rule of Five, (R)-Nigaldipine hydrochloride has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (R)-Nigaldipine hydrochloride?
The CAS number of (R)-Nigaldipine hydrochloride is 189624-85-9.
What is the molecular formula of (R)-Nigaldipine hydrochloride?
The molecular formula of (R)-Nigaldipine hydrochloride is C41H44Cl2N4O6.
What is the molecular weight of (R)-Nigaldipine hydrochloride?
The molecular weight of (R)-Nigaldipine hydrochloride is 758.26 g/mol.
Where can I buy (R)-Nigaldipine hydrochloride?
You can request a quote for (R)-Nigaldipine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (R)-Nigaldipine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for (R)-Nigaldipine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.