(S)-Meclizine
TL;DR: (S)-Meclizine (CAS 189298-47-3) is a chemical compound with molecular formula C25H27ClN2 and molecular weight 390.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(S)-(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
Also Known As: (S)-Meclizine, meclizine, Meclizine, (S)-, Meclozine, (S)-, CAS-1104-22-9
| Molecular Formula | C25H27ClN2 |
|---|---|
| Molecular Weight | 390.19 g/mol |
| LogP | 5.55562 |
| Topological Polar Surface Area | 6.48 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 390.18628 |
| Heavy Atoms | 28 |
| Complexity | 883.9361 |
Chemical Identifiers
| CAS Number | 189298-47-3 |
|---|---|
| SMILES | CC1=CC(=CC=C1)CN2CCN(CC2)[C@@H](C3=CC=CC=C3)C4=CC=C(C=C4)Cl |
Product Overview
(S)-Meclizine (CAS 189298-47-3), with molecular formula C25H27ClN2 and molecular weight 390.19 g/mol. IUPAC: 1-[(S)-(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine.
Chemical Property Profile of (S)-Meclizine
Property Insights of (S)-Meclizine
The XLogP value of 5.55562 indicates that (S)-Meclizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.48 Ų, (S)-Meclizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (S)-Meclizine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (S)-Meclizine?
The CAS number of (S)-Meclizine is 189298-47-3.
What is the molecular formula of (S)-Meclizine?
The molecular formula of (S)-Meclizine is C25H27ClN2.
What is the molecular weight of (S)-Meclizine?
The molecular weight of (S)-Meclizine is 390.19 g/mol.
Where can I buy (S)-Meclizine?
You can request a quote for (S)-Meclizine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (S)-Meclizine?
Yes, KEHONG BIO provides custom synthesis services for (S)-Meclizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.