R-Hydroxyzine
TL;DR: R-Hydroxyzine (CAS 189298-46-2) is a chemical compound with molecular formula C21H27ClN2O2 and molecular weight 374.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol
Also Known As: R-Hydroxyzine, Hydroxyzine, (R)-, (R)-Hydroxyzine, PDSP1_000267, PDSP2_000266
| Molecular Formula | C21H27ClN2O2 |
|---|---|
| Molecular Weight | 374.18 g/mol |
| LogP | 3.0559 |
| Topological Polar Surface Area | 35.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 374.17612 |
| Heavy Atoms | 26 |
| Complexity | 642.8205 |
Chemical Identifiers
| CAS Number | 189298-46-2 |
|---|---|
| SMILES | C1CN(CCN1CCOCCO)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl |
Product Overview
R-Hydroxyzine (CAS 189298-46-2), with molecular formula C21H27ClN2O2 and molecular weight 374.18 g/mol. IUPAC: 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol.
Chemical Property Profile of R-Hydroxyzine
Property Insights of R-Hydroxyzine
The XLogP value of 3.0559 indicates that R-Hydroxyzine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.94 Ų, R-Hydroxyzine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, R-Hydroxyzine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of R-Hydroxyzine?
The CAS number of R-Hydroxyzine is 189298-46-2.
What is the molecular formula of R-Hydroxyzine?
The molecular formula of R-Hydroxyzine is C21H27ClN2O2.
What is the molecular weight of R-Hydroxyzine?
The molecular weight of R-Hydroxyzine is 374.18 g/mol.
Where can I buy R-Hydroxyzine?
You can request a quote for R-Hydroxyzine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for R-Hydroxyzine?
Yes, KEHONG BIO provides custom synthesis services for R-Hydroxyzine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.