4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine
TL;DR: 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine (CAS 188987-81-7) is a chemical compound with molecular formula C9H13FN4 and molecular weight 196.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-fluoro-6-piperidin-1-ylpyrimidin-2-amine
Also Known As: 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine, 4-fluoro-6-(piperidin-1-yl)pyrimidin-2-amine, 4-fluoro-6-piperidin-1-ylpyrimidin-2-amine
| Molecular Formula | C9H13FN4 |
|---|---|
| Molecular Weight | 196.11 g/mol |
| LogP | 1.6 |
| Topological Polar Surface Area | 55.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 196.11243 |
| Heavy Atoms | 14 |
| Complexity | 184.0 |
Chemical Identifiers
| CAS Number | 188987-81-7 |
|---|---|
| SMILES | C1CCN(CC1)C2=CC(=NC(=N2)N)F |
| InChIKey | JHOMLXZSDLLBFN-UHFFFAOYSA-N |
Product Overview
4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine (CAS 188987-81-7), with molecular formula C9H13FN4 and molecular weight 196.11 g/mol. IUPAC: 4-fluoro-6-piperidin-1-ylpyrimidin-2-amine.
Chemical Property Profile of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine
Property Insights of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine. With a topological polar surface area (TPSA) of 55.0 Ų, 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine?
The CAS number of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine is 188987-81-7.
What is the molecular formula of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine?
The molecular formula of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine is C9H13FN4.
What is the molecular weight of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine?
The molecular weight of 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine is 196.11 g/mol.
Where can I buy 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine?
You can request a quote for 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-Fluoro-6-(1-piperidinyl)-2-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.