lorazepam
TL;DR: lorazepam (CAS 18878-17-6) is a chemical compound with molecular formula C19H14Cl2N2O4 and molecular weight 404.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[1-acetyl-7-chloro-5-(2-chlorophenyl)-2-oxo-3H-1,4-benzodiazepin-3-yl] acetate
Also Known As: lorazepam, Lorazepam, N,O-diacetyl-, 3,4'-DICHLOROBIPHENYL, 1-acetyl-3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one, 878A176
| Molecular Formula | C19H14Cl2N2O4 |
|---|---|
| Molecular Weight | 404.03 g/mol |
| LogP | 3.6131 |
| Topological Polar Surface Area | 76.04 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 404.03305 |
| Heavy Atoms | 27 |
| Complexity | 987.425 |
Chemical Identifiers
| CAS Number | 18878-17-6 |
|---|---|
| SMILES | CC(=O)N1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)OC(=O)C)C3=CC=CC=C3Cl |
Product Overview
lorazepam (CAS 18878-17-6), with molecular formula C19H14Cl2N2O4 and molecular weight 404.03 g/mol. IUPAC: [1-acetyl-7-chloro-5-(2-chlorophenyl)-2-oxo-3H-1,4-benzodiazepin-3-yl] acetate.
Chemical Property Profile of lorazepam
Property Insights of lorazepam
The XLogP value of 3.6131 indicates that lorazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.04 Ų falls within the moderate polarity range, balancing permeability and solubility for lorazepam. Following Lipinski's Rule of Five, lorazepam has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of lorazepam?
The CAS number of lorazepam is 18878-17-6.
What is the molecular formula of lorazepam?
The molecular formula of lorazepam is C19H14Cl2N2O4.
What is the molecular weight of lorazepam?
The molecular weight of lorazepam is 404.03 g/mol.
Where can I buy lorazepam?
You can request a quote for lorazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for lorazepam?
Yes, KEHONG BIO provides custom synthesis services for lorazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.