3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- structure

3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-

TL;DR: 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- (CAS 188637-86-7) is a chemical compound with molecular formula C28H28ClN5O5S3 and molecular weight 645.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[2-[2-[[2-[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydrobenzo[e]indol-3-yl]-2-oxoacetyl]amino]ethyl]-1,3-thiazol-4-yl]-N-(3-methylsulfinylpropyl)-1,3-thiazole-4-carboxamide

Also Known As: 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-, 2'-(2-{2-[(1S)-1-(Chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]-2-oxoacetamido}ethyl)-N-[3-(methanesulfinyl)propyl][2,4'-bi-1,3-thiazole]-4-carboximidic acid, 2'-(2-{2-[1-(Chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl](oxo)acetamido}ethyl)-N-[3-(methanesulfinyl)propyl][2,4'-bi-1,3-thiazole]-4-carboximidic acid, 2-[2-[2-[[2-[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydrobenzo[e]indol-3-yl]-2-oxoacetyl]amino]ethyl]-1,3-thiazol-4-yl]-N-(3-methylsulfinylpropyl)-1,3-thiazole-4-carboxamide

CAS: 188637-86-7
Molecular Formula C28H28ClN5O5S3
Molecular Weight 645.09 g/mol
LogP 3.1
Topological Polar Surface Area 217.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 10
Rotatable Bonds 10
Exact Mass 645.0941
Heavy Atoms 42
Complexity 1010.0

Chemical Identifiers

CAS Number 188637-86-7
SMILES CS(=O)CCCNC(=O)C1=CSC(=N1)C2=CSC(=N2)CCNC(=O)C(=O)N3C[C@H](C4=C3C=C(C5=CC=CC=C54)O)CCl
InChIKey CIRBMLRXAWKDPG-MRIBLNRYSA-N

Product Overview

3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- (CAS 188637-86-7), with molecular formula C28H28ClN5O5S3 and molecular weight 645.09 g/mol. IUPAC: 2-[2-[2-[[2-[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydrobenzo[e]indol-3-yl]-2-oxoacetyl]amino]ethyl]-1,3-thiazol-4-yl]-N-(3-methylsulfinylpropyl)-1,3-thiazole-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-

XLogP
3.1
TPSA (Topological Polar Surface Area)
217.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
10
Rotatable Bonds
10
Heavy Atoms
42
Complexity
1010.0
Exact Mass
645.0941
Monoisotopic Mass
645.0941
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-

The XLogP value of 3.1 indicates that 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 217.0 Ų indicates high polarity, suggesting 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-?

The CAS number of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- is 188637-86-7.

What is the molecular formula of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-?

The molecular formula of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- is C28H28ClN5O5S3.

What is the molecular weight of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-?

The molecular weight of 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- is 645.09 g/mol.

Where can I buy 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-?

You can request a quote for 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)-?

Yes, KEHONG BIO provides custom synthesis services for 3H-Benz(e)indole-3-acetamide, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-N-(2-(4-(((3-(methylsulfinyl)propyl)amino)carbonyl)(2,4'-bithiazol)-2'-yl)ethyl)-alpha-oxo-, (1S)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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