5-Propynyluridine
TL;DR: 5-Propynyluridine (CAS 188254-39-9) is a chemical compound with molecular formula C12H14N2O6 and molecular weight 282.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
Also Known As: 5-propynyluridine, 5-propynyl uracil, Zonavir, 5-(1-propynyl)uridine, Uridine, 5-(1-propynyl)-
| Molecular Formula | C12H14N2O6 |
|---|---|
| Molecular Weight | 282.09 g/mol |
| LogP | -2.4805 |
| Topological Polar Surface Area | 124.78 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 282.08517 |
| Heavy Atoms | 20 |
| Complexity | 666.99585 |
Chemical Identifiers
| CAS Number | 188254-39-9 |
|---|---|
| SMILES | CC#CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Product Overview
5-Propynyluridine (CAS 188254-39-9), with molecular formula C12H14N2O6 and molecular weight 282.09 g/mol. IUPAC: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione.
Chemical Property Profile of 5-Propynyluridine
Property Insights of 5-Propynyluridine
The XLogP value of -2.4805 indicates that 5-Propynyluridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 124.78 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Propynyluridine. Following Lipinski's Rule of Five, 5-Propynyluridine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Propynyluridine?
The CAS number of 5-Propynyluridine is 188254-39-9.
What is the molecular formula of 5-Propynyluridine?
The molecular formula of 5-Propynyluridine is C12H14N2O6.
What is the molecular weight of 5-Propynyluridine?
The molecular weight of 5-Propynyluridine is 282.09 g/mol.
Where can I buy 5-Propynyluridine?
You can request a quote for 5-Propynyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Propynyluridine?
Yes, KEHONG BIO provides custom synthesis services for 5-Propynyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.