Henningsoline structure

Henningsoline

TL;DR: Henningsoline (CAS 18797-85-8) is a chemical compound with molecular formula C22H26N2O5 and molecular weight 398.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(9,14-dihydroxy-8-methoxy-15-oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5(10),6,8,17-tetraen-11-yl)ethanone

Also Known As: HENNINGSOLINE, 1-(9,14-dihydroxy-8-methoxy-15-oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5(10),6,8,17-tetraen-11-yl)ethanone, 1-(12,17-Dihydroxy-11-methoxy-19,20-didehydro-17,18-epoxycuran-1-yl)ethan-1-one, 1-(9,14-dihydroxy-8-methoxy-15-oxa-1,11-diazahexacyclo(16.3.1.04,12.04,21.05,10.013,19)docosa-5(10),6,8,17-tetraen-11-yl)ethanone, RefChem:347101

CAS: 18797-85-8
Molecular Formula C22H26N2O5
Molecular Weight 398.18 g/mol
LogP 0.4
Topological Polar Surface Area 82.5 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 398.18417
Heavy Atoms 29
Complexity 757.0

Chemical Identifiers

CAS Number 18797-85-8
SMILES CC(=O)N1C2C3C4CC5C2(CCN5CC4=CCOC3O)C6=C1C(=C(C=C6)OC)O
InChIKey BCKDRLNZTWKJHT-UHFFFAOYSA-N

Product Overview

Henningsoline (CAS 18797-85-8), with molecular formula C22H26N2O5 and molecular weight 398.18 g/mol. IUPAC: 1-(9,14-dihydroxy-8-methoxy-15-oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5(10),6,8,17-tetraen-11-yl)ethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Henningsoline

XLogP
0.4
TPSA (Topological Polar Surface Area)
82.5
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
29
Complexity
757.0
Exact Mass
398.18417
Monoisotopic Mass
398.18417
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Henningsoline

The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Henningsoline. The TPSA of 82.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Henningsoline. Following Lipinski's Rule of Five, Henningsoline has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Henningsoline?

The CAS number of Henningsoline is 18797-85-8.

What is the molecular formula of Henningsoline?

The molecular formula of Henningsoline is C22H26N2O5.

What is the molecular weight of Henningsoline?

The molecular weight of Henningsoline is 398.18 g/mol.

Where can I buy Henningsoline?

You can request a quote for Henningsoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Henningsoline?

Yes, KEHONG BIO provides custom synthesis services for Henningsoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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