Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide structure

Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide

TL;DR: Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide (CAS 18724-73-7) is a chemical compound with molecular formula C16H22N6O4S and molecular weight 394.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[3-(1H-imidazol-5-yl)-2-[(6-oxopiperidine-2-carbonyl)amino]propanoyl]-1,3-thiazolidine-4-carboxamide

Also Known As: Pyro-aad-his-tzl-NH2, MK 771, MK771, Pyro-2-aminoadipylhistidylthiazolidine-4-carboxyamide, Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide

CAS: 18724-73-7
Molecular Formula C16H22N6O4S
Molecular Weight 394.14 g/mol
LogP -2.1
Topological Polar Surface Area 176.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 394.14233
Heavy Atoms 27
Complexity 618.0

Chemical Identifiers

CAS Number 18724-73-7
SMILES C1CC(NC(=O)C1)C(=O)NC(CC2=CN=CN2)C(=O)N3CSCC3C(=O)N
InChIKey OGUDACTYCTVDNZ-UHFFFAOYSA-N

Product Overview

Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide (CAS 18724-73-7), with molecular formula C16H22N6O4S and molecular weight 394.14 g/mol. IUPAC: 3-[3-(1H-imidazol-5-yl)-2-[(6-oxopiperidine-2-carbonyl)amino]propanoyl]-1,3-thiazolidine-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide

XLogP
-2.1
TPSA (Topological Polar Surface Area)
176.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
27
Complexity
618.0
Exact Mass
394.14233
Monoisotopic Mass
394.14233
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide

The XLogP value of -2.1 indicates that Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 176.0 Ų indicates high polarity, suggesting Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide?

The CAS number of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide is 18724-73-7.

What is the molecular formula of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide?

The molecular formula of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide is C16H22N6O4S.

What is the molecular weight of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide?

The molecular weight of Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide is 394.14 g/mol.

Where can I buy Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide?

You can request a quote for Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide?

Yes, KEHONG BIO provides custom synthesis services for Pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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