6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol
TL;DR: 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol (CAS 18706-23-5) is a chemical compound with molecular formula C10H4Cl2F3NO and molecular weight 280.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,8-dichloro-2-(trifluoromethyl)-1H-quinolin-4-one
Also Known As: 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol, 6,8-dichloro-2-(trifluoromethyl)-1H-quinolin-4-one, 6,8-Dichloro-2-trifluoromethyl-4-quinolinol, 6,8-dichloro-2-(trifluoromethyl)-4-Quinolinol, B-7572
| Molecular Formula | C10H4Cl2F3NO |
|---|---|
| Molecular Weight | 280.96 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 280.9622 |
| Heavy Atoms | 17 |
| Complexity | 369.0 |
Chemical Identifiers
| CAS Number | 18706-23-5 |
|---|---|
| SMILES | C1=C(C=C(C2=C1C(=O)C=C(N2)C(F)(F)F)Cl)Cl |
| InChIKey | AZADALPYSVBIQC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol (CAS 18706-23-5), with molecular formula C10H4Cl2F3NO and molecular weight 280.96 g/mol. IUPAC: 6,8-dichloro-2-(trifluoromethyl)-1H-quinolin-4-one.
Chemical Property Profile of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol
Property Insights of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol
The XLogP value of 3.7 indicates that 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol?
The CAS number of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol is 18706-23-5.
What is the molecular formula of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol?
The molecular formula of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol is C10H4Cl2F3NO.
What is the molecular weight of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol?
The molecular weight of 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol is 280.96 g/mol.
Where can I buy 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol?
You can request a quote for 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 6,8-Dichloro-2-(trifluoromethyl)quinolin-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.