Pafuramidine
TL;DR: Pafuramidine (CAS 186953-56-0) is a chemical compound with molecular formula C20H20N4O3 and molecular weight 364.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N'-methoxy-4-[5-[4-(N'-methoxycarbamimidoyl)phenyl]furan-2-yl]benzenecarboximidamide
Also Known As: Pafuramidine, DB289, 4,4'-(Furan-2,5-diyl)bis(N-methoxybenzimidamide), 4,4'-(Furan-2,5-diyl)bis(N'-methoxybenzene-1-carboximidamide), N'-methoxy-4-[5-[4-[(Z)-N'-methoxycarbamimidoyl]phenyl]furan-2-yl]benzenecarboximidamide
| Molecular Formula | C20H20N4O3 |
|---|---|
| Molecular Weight | 364.15 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 108.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 364.15353 |
| Heavy Atoms | 27 |
| Complexity | 477.0 |
Chemical Identifiers
| CAS Number | 186953-56-0 |
|---|---|
| SMILES | CON=C(C1=CC=C(C=C1)C2=CC=C(O2)C3=CC=C(C=C3)C(=NOC)N)N |
| InChIKey | UKOQVLAXCBRRGH-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Pafuramidine (CAS 186953-56-0), with molecular formula C20H20N4O3 and molecular weight 364.15 g/mol. IUPAC: N'-methoxy-4-[5-[4-(N'-methoxycarbamimidoyl)phenyl]furan-2-yl]benzenecarboximidamide.
Chemical Property Profile of Pafuramidine
Property Insights of Pafuramidine
The XLogP value of 3.2 indicates that Pafuramidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 108.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Pafuramidine. Following Lipinski's Rule of Five, Pafuramidine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pafuramidine?
The CAS number of Pafuramidine is 186953-56-0.
What is the molecular formula of Pafuramidine?
The molecular formula of Pafuramidine is C20H20N4O3.
What is the molecular weight of Pafuramidine?
The molecular weight of Pafuramidine is 364.15 g/mol.
Where can I buy Pafuramidine?
You can request a quote for Pafuramidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pafuramidine?
Yes, KEHONG BIO provides custom synthesis services for Pafuramidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.