J1.008.536E structure

J1.008.536E

TL;DR: J1.008.536E (CAS 186802-35-7) is a chemical compound with molecular formula C17H18FN3O4 and molecular weight 347.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-6-[(3S)-3-aminopyrrolidin-1-yl]-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

Also Known As: J1.008.536E, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-((3S)-3-amino-1-pyrrolidinyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-, 10-(3(S)-Amino-1-pyrrolidinyl)-9-fluoro-2,3-dihydro-3(S)-methyl-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine-6-carbocylic acid, [(3S)-3-aminopyrrolidin-1-yl]-fluoro-methyl-oxo-[?]carboxylic acid, (2S)-6-[(3S)-3-aminopyrrolidin-1-yl]-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

CAS: 186802-35-7
Molecular Formula C17H18FN3O4
Molecular Weight 347.13 g/mol
LogP -0.9
Topological Polar Surface Area 96.1 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 8
Rotatable Bonds 2
Exact Mass 347.12814
Heavy Atoms 25
Complexity 627.0

Chemical Identifiers

CAS Number 186802-35-7
SMILES C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CC[C@@H](C4)N)F)C(=O)O
InChIKey GOQMLVCAKGZQKN-IUCAKERBSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (8 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

J1.008.536E (CAS 186802-35-7), with molecular formula C17H18FN3O4 and molecular weight 347.13 g/mol. IUPAC: (2S)-6-[(3S)-3-aminopyrrolidin-1-yl]-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of J1.008.536E

XLogP
-0.9
TPSA (Topological Polar Surface Area)
96.1
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
8
Rotatable Bonds
2
Heavy Atoms
25
Complexity
627.0
Exact Mass
347.12814
Monoisotopic Mass
347.12814
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of J1.008.536E

The XLogP value of -0.9 indicates that J1.008.536E is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 96.1 Ų falls within the moderate polarity range, balancing permeability and solubility for J1.008.536E. Following Lipinski's Rule of Five, J1.008.536E has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of J1.008.536E?

The CAS number of J1.008.536E is 186802-35-7.

What is the molecular formula of J1.008.536E?

The molecular formula of J1.008.536E is C17H18FN3O4.

What is the molecular weight of J1.008.536E?

The molecular weight of J1.008.536E is 347.13 g/mol.

Where can I buy J1.008.536E?

You can request a quote for J1.008.536E directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for J1.008.536E?

Yes, KEHONG BIO provides custom synthesis services for J1.008.536E and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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