H4 SALEN structure

H4 SALEN

TL;DR: H4 SALEN (CAS 186537-85-9) is a chemical compound with molecular formula C28H37N3O5S and molecular weight 527.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide

Also Known As: H4 SALEN, Je 533, 4-Thiazolidinecarboxamide, N-(1,1-dimethylethyl)-3-((2S,3S)-2-hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-1-oxo-4-phenylbutyl)-5,5-dimethyl-,(4R)-, (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide

CAS: 186537-85-9
Molecular Formula C28H37N3O5S
Molecular Weight 527.25 g/mol
LogP 3.6
Topological Polar Surface Area 144.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 6
Rotatable Bonds 8
Exact Mass 527.2454
Heavy Atoms 37
Complexity 823.0

Chemical Identifiers

CAS Number 186537-85-9
SMILES CC1=C(C=CC=C1O)C(=O)N[C@@H](CC2=CC=CC=C2)[C@@H](C(=O)N3CSC([C@H]3C(=O)NC(C)(C)C)(C)C)O
InChIKey CGFVYUGIPISJQG-ACIOBRDBSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (9 patents) Peptides & Amino Acids (2 patents) Pharmaceutical Intermediates (8 patents)

Product Overview

H4 SALEN (CAS 186537-85-9), with molecular formula C28H37N3O5S and molecular weight 527.25 g/mol. IUPAC: (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of H4 SALEN

XLogP
3.6
TPSA (Topological Polar Surface Area)
144.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
6
Rotatable Bonds
8
Heavy Atoms
37
Complexity
823.0
Exact Mass
527.2454
Monoisotopic Mass
527.2454
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of H4 SALEN

The XLogP value of 3.6 indicates that H4 SALEN is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 144.0 Ų indicates high polarity, suggesting H4 SALEN may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, H4 SALEN has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of H4 SALEN?

The CAS number of H4 SALEN is 186537-85-9.

What is the molecular formula of H4 SALEN?

The molecular formula of H4 SALEN is C28H37N3O5S.

What is the molecular weight of H4 SALEN?

The molecular weight of H4 SALEN is 527.25 g/mol.

Where can I buy H4 SALEN?

You can request a quote for H4 SALEN directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for H4 SALEN?

Yes, KEHONG BIO provides custom synthesis services for H4 SALEN and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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