ZD 1611 structure

ZD 1611

TL;DR: ZD 1611 (CAS 186497-38-1) is a chemical compound with molecular formula C22H24N4O5S and molecular weight 456.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[4-[3-[(3-methoxy-5-methylpyrazin-2-yl)sulfamoyl]-2-pyridinyl]phenyl]-2,2-dimethylpropanoic acid

Also Known As: ZD 1611, 3-[4-[3-[(3-methoxy-5-methylpyrazin-2-yl)sulfamoyl]pyridin-2-yl]phenyl]-2,2-dimethylpropanoic acid, J1.178.588C, 3-(4-(3-(N-(3-Methoxy-5-methylpyrazin-2-yl)sulfamoyl)pyridin-2-yl)phenyl)-2,2-dimethylpropanoic acid, 2-[4-(2-carboxy-2-methylpropyl)phenyl]-N-(3-methoxy-5-methylpyrazin-2-yl)pyridine-3-sulphonamide

CAS: 186497-38-1
Molecular Formula C22H24N4O5S
Molecular Weight 456.15 g/mol
LogP 3.30972
Topological Polar Surface Area 131.37 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 8
Exact Mass 456.14673
Heavy Atoms 32
Complexity 1241.4309

Chemical Identifiers

CAS Number 186497-38-1
SMILES CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)CC(C)(C)C(=O)O

Product Overview

ZD 1611 (CAS 186497-38-1), with molecular formula C22H24N4O5S and molecular weight 456.15 g/mol. IUPAC: 3-[4-[3-[(3-methoxy-5-methylpyrazin-2-yl)sulfamoyl]-2-pyridinyl]phenyl]-2,2-dimethylpropanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of ZD 1611

XLogP
3.30972
TPSA (Topological Polar Surface Area)
131.37
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
8
Heavy Atoms
32
Complexity
1241.4309
Exact Mass
456.14673
Monoisotopic Mass
456.14673
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of ZD 1611

The XLogP value of 3.30972 indicates that ZD 1611 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 131.37 Ų falls within the moderate polarity range, balancing permeability and solubility for ZD 1611. Following Lipinski's Rule of Five, ZD 1611 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of ZD 1611?

The CAS number of ZD 1611 is 186497-38-1.

What is the molecular formula of ZD 1611?

The molecular formula of ZD 1611 is C22H24N4O5S.

What is the molecular weight of ZD 1611?

The molecular weight of ZD 1611 is 456.15 g/mol.

Where can I buy ZD 1611?

You can request a quote for ZD 1611 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for ZD 1611?

Yes, KEHONG BIO provides custom synthesis services for ZD 1611 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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