Ingliforib
TL;DR: Ingliforib (CAS 186392-65-4) is a chemical compound with molecular formula C23H24ClN3O5 and molecular weight 457.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-[(2S,3R)-4-[(3S,4R)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-1H-indole-2-carboxamide
Also Known As: Ingliforib, ingliforibum, Ingliforib [USAN], Ingliforib [USAN:INN], INGLIFORIB [INN]
| Molecular Formula | C23H24ClN3O5 |
|---|---|
| Molecular Weight | 457.14 g/mol |
| LogP | 1.0873 |
| Topological Polar Surface Area | 125.89 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 457.14044 |
| Heavy Atoms | 32 |
| Complexity | 1109.2772 |
Chemical Identifiers
| CAS Number | 186392-65-4 |
|---|---|
| SMILES | C1[C@H]([C@H](CN1C(=O)[C@@H]([C@H](CC2=CC=CC=C2)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl)O)O)O |
Product Overview
Ingliforib (CAS 186392-65-4), with molecular formula C23H24ClN3O5 and molecular weight 457.14 g/mol. IUPAC: 5-chloro-N-[(2S,3R)-4-[(3S,4R)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-1H-indole-2-carboxamide.
Chemical Property Profile of Ingliforib
Property Insights of Ingliforib
The XLogP value of 1.0873 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Ingliforib. The TPSA of 125.89 Ų falls within the moderate polarity range, balancing permeability and solubility for Ingliforib. Following Lipinski's Rule of Five, Ingliforib has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ingliforib?
The CAS number of Ingliforib is 186392-65-4.
What is the molecular formula of Ingliforib?
The molecular formula of Ingliforib is C23H24ClN3O5.
What is the molecular weight of Ingliforib?
The molecular weight of Ingliforib is 457.14 g/mol.
Where can I buy Ingliforib?
You can request a quote for Ingliforib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ingliforib?
Yes, KEHONG BIO provides custom synthesis services for Ingliforib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.