Cryptophycin 52
TL;DR: Cryptophycin 52 (CAS 186256-67-7) is a chemical compound with molecular formula C36H45ClN2O8 and molecular weight 668.29 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,10R,13E,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-6,6-dimethyl-3-(2-methylpropyl)-16-[(1S)-1-[(2R,3R)-3-phenyloxiran-2-yl]ethyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
Also Known As: Cryptophycin 52, CRYPTOPHYCIN-52 [MI], (+)-CRYPTOPHYCIN 52, CRYPTOPHYCIN 52, (+)-, (3S,10R,13E,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-6,6-dimethyl-3-(2-methylpropyl)-16-[(1S)-1-[(2R,3R)-3-phenyloxiran-2-yl]ethyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
| Molecular Formula | C36H45ClN2O8 |
|---|---|
| Molecular Weight | 668.29 g/mol |
| LogP | 5.1241 |
| Topological Polar Surface Area | 132.56 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 668.28644 |
| Heavy Atoms | 47 |
| Complexity | 1460.1368 |
Chemical Identifiers
| CAS Number | 186256-67-7 |
|---|---|
| SMILES | C[C@@H]([C@@H]1C/C=C/C(=O)N[C@@H](C(=O)NCC(C(=O)O[C@H](C(=O)O1)CC(C)C)(C)C)CC2=CC(=C(C=C2)OC)Cl)[C@@H]3[C@H](O3)C4=CC=CC=C4 |
Product Overview
Cryptophycin 52 (CAS 186256-67-7), with molecular formula C36H45ClN2O8 and molecular weight 668.29 g/mol. IUPAC: (3S,10R,13E,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-6,6-dimethyl-3-(2-methylpropyl)-16-[(1S)-1-[(2R,3R)-3-phenyloxiran-2-yl]ethyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone.
Chemical Property Profile of Cryptophycin 52
Property Insights of Cryptophycin 52
The XLogP value of 5.1241 indicates that Cryptophycin 52 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 132.56 Ų falls within the moderate polarity range, balancing permeability and solubility for Cryptophycin 52. Following Lipinski's Rule of Five, Cryptophycin 52 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cryptophycin 52?
The CAS number of Cryptophycin 52 is 186256-67-7.
What is the molecular formula of Cryptophycin 52?
The molecular formula of Cryptophycin 52 is C36H45ClN2O8.
What is the molecular weight of Cryptophycin 52?
The molecular weight of Cryptophycin 52 is 668.29 g/mol.
Where can I buy Cryptophycin 52?
You can request a quote for Cryptophycin 52 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cryptophycin 52?
Yes, KEHONG BIO provides custom synthesis services for Cryptophycin 52 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.